Asbestosis mesothelioma affects the parenchyma tissue of the lungs and it is caused due to over exposure to asbestos particles. Hence it is a work related malady like mesothelioma cancer. The parenchymal tissues would permanently remain painful and irritable causing dyspnea or shortness of breath. Here lies enhanced chances of contracting lung cancer. Over exposure to asbestos would result in formation of plaque above the diaphragm and it can be found out in X-ray tests.
Asbestosis mesothelioma victims witness breathing difficulties as the initial symptom. Total respiratory failure may be experienced by patients who are seriously affected. Minimum ten years are required for the disease to become visible. But many cases have been reported where the illness became noticeable just after a period of three months. Amphibole and Serpentine are the two types of asbestos particles. Amphibole is thin and straight whereas serpentine is curved. It is the first one that is responsible for the disease since it can move deep into the lungs through the process of inhalation. This results in injuring lung tissues around terminal bronchioles and alveolar ducts.
The asbestos fibers enter the air sacs of alveoli, where oxygen is routed into the blood. There they rouse the lung's inbuilt immune system into getting swollen with the aim of rejecting the foreign body. To get the intruder digested, the body releases macrophages, but asbestos being indigestible, the macrophages tend to die. The result would be the release of cytokines, which further invite more macrophages. This extra accumulation results in thickening of alveolar walls. The elasticity of the walls and transmission of gases get reduced hindering oxygen transfer into the blood.
Those who are seriously affected by asbestosis mesothelioma may suffer from clubbing of fingers and inspiratory crackles. The disease may not be posing threat to life, but it can result in serious medical conditions like heart failure. Development of plaque in the chest and lung cavities is found in almost half of the patients.
The disease has no treatment for a complete cure presently, but administering regular oxygen therapy at home can relieve breathing problems. Chest percussion, respiratory physiotherapy, vibration and nebulization are also utilized to attenuate secretions causing shortness of breath. Like mesothelioma patients, asbestosis patients are also entitled for compensation from their erstwhile employers.
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